{"id":1188,"date":"2016-02-02T16:57:18","date_gmt":"2016-02-02T16:57:18","guid":{"rendered":"http:\/\/blogs.kent.ac.uk\/biosciences\/?p=1188"},"modified":"2016-02-02T16:57:18","modified_gmt":"2016-02-02T16:57:18","slug":"research-seminar-how-to-keep-you-endosymbiont-under-control","status":"publish","type":"post","link":"https:\/\/blogs.kent.ac.uk\/biosciences\/2016\/02\/02\/research-seminar-how-to-keep-you-endosymbiont-under-control\/","title":{"rendered":"Research Seminar: How to keep you endosymbiont under control"},"content":{"rendered":"

Dr. Lilach Sheiner, Institute of Infection, Immunity and Inflammation, University of Glasgow<\/strong><\/p>\n

Tuesday 9th February, 1.00 p.m., Cornwallis Octagon Lecture Theatre 2 (COLT2)<\/strong><\/p>\n

Apicomplexa parasites are global killers causing human and animal diseases like malaria and toxoplasmosis. These eukaryotic protozoan posses two organelles of endosymbiotic origin: a relict plats named the apicoplast and a mitochondrion. We are interested in the mechainism allowing the remarkable tight synchrony and collaboration between both symbionts and parasite cell cycle and with eachother.<\/p>\n

An important aspect of this interaction in that the nuclear genome hosts the majority of the genes encoding the symbiont\u2019s proteomes. I will present new insights on how proteins that are encoded in the nuclear genome gain entry into the apicoplast and how this is controlled. Specifically, we explored the role of a potentially new redox pathway in controlling protein import into the apicoplast of T. <\/i>gondii<\/i> via oxidative folding.<\/p>\n