Dr. Anne-Marie Seymour, School of Biological, Biomedical & Environmental Sciences, University of Hull
Tuesday 16th February, 1.00 p.m., Cornwallis Octagon Lecture Theatre 2
Cardiac hypertrophy is a major risk factor in the development of heart failure and is associated with significant cellular and structural remodelling. Understanding the mechanisms involved in the adaptations in hypertrophy and the transition to heart failure will help to identify new targets for treatment.
Molecular imaging is likely to play an increasingly important role in predicting and detecting these adaptations and in guiding treatment in patients. We have been applying in vivo methods for detecting early markers of hypertrophy and their responses to therapy including metabolic imaging with hyperpolarized 13C labelled substrates and 18F Positron emission tomography (PET).